Antipsychotics and Pregnancy Outcome
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چکیده
New safety information has been added to the prescribing information for desipramine (Norpramin). The updated label now states "extreme caution should be used when this drug is given to patients who have a family history of sudden death, cardiac dysrhythmias, and cardiac conduction disturbances; and that seizures precede cardiac dysrhythmias and death in some patients." The label also warns that rates of death associated with desipramine overdose are higher than those of other tricyclic antidepressants. Additional information has been added to help identify and manage overdose.
منابع مشابه
Antipsychotics during pregnancy: relation to fetal and maternal metabolic effects.
CONTEXT Knowledge about the effects of exposure to the newer antipsychotics during pregnancy is limited. OBJECTIVE To investigate the effects of maternal use of antipsychotics during pregnancy on gestational diabetes and fetal growth. DESIGN Population-based cohort study comparing women exposed and not exposed to antipsychotics during pregnancy. Exposure was defined as prescriptions filled....
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BACKGROUND Women prescribed antipsychotics face the dilemma on whether to continue medication in pregnancy in terms of balancing risks and benefits. Previous research on other psychotropic medications suggests that many women discontinue treatment in early pregnancy. However, very limited evidence exists on discontinuation of antipsychotic medication. METHODS We identified 495,953 pregnant wo...
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BACKGROUND The gold standard pharmacological agents used to treat schizophrenia and bipolar disorder in adults are antipsychotics. Atypical or second-generation antipsychotics have superseded or used as alternatives to typical first-generation antipsychotics due to better tolerability and safety profile. However the efficacy and safety of these drugs are severely limited in pregnancy and/or wom...
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OBJECTIVE Both first- (FGAs) and second-generation antipsychotics (SGAs) are routinely used in treating severe and persistent psychiatric disorders. However, until now no articles have analyzed systematically the safety of both classes of psychotropics during pregnancy. DATA SOURCES AND SEARCH STRATEGY: Medical literature information published in any language since 1950 was identified using MED...
متن کاملPregnancy and atypical antipsychotics.
Scientific research aiming at discovering new generations of effective medications is a common practice in medicine, and psychiatric research is no exception. Antipsychotics are used to treat chronic mental illnesses such as schizophrenia. The new generation of antipsychotics (atypicals) gradually reveal their advantages in comparison to the older generation of antipsychotics (conventional, typ...
متن کاملAtypical antipsychotics, maternal and child outcomes: A critical review
Introduction Atypical antipsychotics are increasingly prescribed for women suffering affective and non-affective psychoses during the antenatal and postnatal period. The level of evidence for psychopharmacological treatment during pregnancy with these agents is generally poor, especially on maternal, foetal and infant outcomes. The aim is to summarize the current evidence on the use of atypical...
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